Tracking Plasma Lactate Concentration in Vivo with a Catheter-Tip L-Lactate Sensor

Authors

Brett T. Weinzapfel, Rose-Hulman Institute of Technology
Mark D. Ball, Rose-Hulman Institute of Technology
Lee R. Waite, Rose-Hulman Institute of TechnologyFollow
Nacer E. Abrouk, Rose-Hulman Institute of Technology
Shun P. Lim, Rose-Hulman Institute of Technology

Document Type

Article

Publication Date

3-1993

Abstract

To circumvent the problems of repeated blood sampling for in vitro analysis, a catheter-tip L-lactate sensor has been developed. The sensor was tested in anesthetized pigs (n=6). The sensor in vivo tracked the lactate concentration non-linearly, seeming to obey Michaelis-Menten kinetics. Calibration time was short, typically 1.5 min per lactate standard. Furthermore, time drift was small, typically -1.3% to -3.3% per hour of in vivo use.

Comments

MSTR 93-03

Recommended Citation

Weinzapfel, Brett T.; Ball, Mark D.; Waite, Lee R.; Abrouk, Nacer E.; and Lim, Shun P., "Tracking Plasma Lactate Concentration in Vivo with a Catheter-Tip L-Lactate Sensor" (1993). Mathematical Sciences Technical Reports (MSTR). 83.
https://scholar.rose-hulman.edu/math_mstr/83